Acne Vulgaris
1. Identification
Skin Lesion: Polymorphic presentation including comedones (open/blackheads or closed/whiteheads), papules, pustules, and in severe cases, nodules and cysts.
Severity Grading:
- Mild: Many comedones, papules and pustules.
- Moderate: Numerous comedones, papules and pustules.
- Severe: Covered with comedones, numerous pustules and papules, a few nodules and cyst.
2. Differential Diagnosis
Acne Rosacea
- The Clue: Facial flushing, persistent erythema, and telangiectasia. Triggers include spicy food, heat, and alcohol.
- Vs Acne: Rosacea lacks comedones. It primarily affects the central face (nose, cheeks, forehead) in adults aged 30-50.
Perioral Dermatitis
- The Clue: Small, inflammatory papules around the mouth with a characteristic clear zone (sparing) at the lip margin (vermilion border).
- Vs Acne: Often triggered by the use of topical steroids on the face. Does not feature comedones.
3. Management
Mild Acne:
- Benzoyl Peroxide 5%: Apply daily.
- Topical Retinoids (Adapalene 0.1%): Apply at night. Contraindicated in pregnancy!
- Step up to moderate acne management if no improvement after 3 months
Moderate Acne:
- Choose 2 from these: Benzoyl peroxide | Retinoid | Topical antibiotic | Azelaic acid | Salicylic acid
- ADD ON ONE ORAL ANTIBIOTIC IF NO IMPROVEMENT AFTER 3 MONTHS. Response to oral antibiotics should be assessed at 6 - 8 weeks. Recommended duration of oral antibiotics is 3 - 4 months.
- Doxycycline: 100mg OD for 12 weeks.
- Erythromycin: 400mg BD for 12 weeks. (Safe in pregnancy).
Severe Acne:
- Refer dermatology
⚠️ Clinical Pearl: To avoid antibiotic resistance, never use oral antibiotics as monotherapy; always combine with a topical agent like Benzoyl Peroxide or Adapalene.